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The epidemiological data on sex differences in acetaminophen-induced liver injury in humans is inconsistent, which can be attributed to confounding factors such as variations in age, dosage, time elapsed from ingestion to hospitalization, and time from ingestion to N-acetylcysteine administration

Previous studies have shown that PGPIPN could play an important role in immune response in rats and mice, such as promoting macrophage phagocytosis and lymphocyte proliferation [14]

In some studies, researchers have people take up to 3,000 milligrams a day, divided into two or three doses

Injectable users rarely experience these effects at standard therapeutic doses